Anicia Juliana was an important aristocratic woman during the reigns of Anastasius, Justin and Justinian. She was the daughter of the Emperor of the West, Flavius Anicius Olybrius and the granddaughter of Valentinian III. She was the sole patron of the lavish Church of Hagios Polyeuktos built by the year 527, which was a modeled on Solomon’s Temple in Jerusalem. 
The life of Anicia Juliana is known to us in some detail. She was born around A.D. 463 to Flavius Anicius Olybrius (who was Emperor of the West in 472) and Placidia the younger, daughter of Valentinian III. In 479 she was offered in marriage to Theodoric the Amal, but this match did not take place. Soon thereafter she was married to Flavius Areobindus Dagalaifus with whom she had only one son, Flavius Anicius Olybrius Junior who was consul in the East as a very young boy in 491. The latter had at least two daughters and presumably no son. Areobindus was still alive in 512 when the crown was pressed upon him in the course of a popular riot against the Emperor Anastasius, an honor which he avoided by flight. Juliana is known to have built other churches in addition to Hagios Polyeuktos. Juliana died around 527 early in the reign of Justinian.
After Anicia Juliana's death, it is accorded that her son Olybrius was somehow implicated in the Nika riots of 532 and was exiled by Justinian, who confiscated his property (presumably including the palace and church). Some years later he was allowed to return, and his property was restored to him. Nothing further is heard of this ancient and illustrious family, which must be supposed to have died out.