Poimanenon (Ποιμανηνόν) was a city, fortress and bishopric in Hellespont in the northern foothills of the Mysian highlands. It was probably home to a notable temple to Asclepius in the Classical era. It became a strategic point beginning in the Komnenian period. Turkish raids reached the area in 1113. At the end of 1204, Theodore Laskaris was defeated near Poimanenon by Latin troops, who then captured the fortress of Poimanenon. John III Vatatzes defeated a coalition of Latins in 1224. It perhaps fell to the Karesi Principality, and was firmly under Ottoman control in the 1330s. The settlement here moved to the nearby town Soğuksu (historically [Eski] Manyas) around 1700. The remains of a large castle along with early Ottoman mosque and türbe have survived at the site.