The Monastery of Christ at Chora (Μονή του Χριστού της Χώρα) was located in northwestern Byzantine Constantinople (modern Istanbul, Turkey) near Charisios Gate (Edirnekapı), south of the Palace of the Porphyrogenitus (Tekfur Sarayı). The well-preserved mosaics and frescoes of the surviving katholikon of the monastery are important examples of monumental art of the Late Byzantine period. After serving as a mosque (known as Kariye Mosque or Ali Pasha Kenise Mosque), it was converted into a museum in 1945 and is now part of the Historic Areas of Istanbul of UNESCO World Heritage. 

The rural character of the site seems to account for the name chora (χώρα), which can be interpreted as “land” or “in the country”. The site was originally outside the city walls built by Constantine, but also would have continued to be sparsely inhabited even during much of the Ottoman era. The word chora can also mean “dwelling place”, and may have been interpreted in a mystical sense. Inscriptions of its decoration identifies Christ as “the land of the living” and the Virgin as “the container of the uncontainable”, both of which involve a play on the word chora.
The early history of Chora is obscure due in part to the many contradictions in the sources. According to one tradition, the relics of St. Babylas were located here in the early 4th century. Another tradition attributes its foundation to St. Theodore, an uncle of Theodora, the wife of Justinian I. A more reliable founder is general Crispus, the son-in-law of Emperor Phocas, who supposedly founded the monastery in the 7th century when Heraclius forced him to retire. The earliest archaeological evidence is the vaulted substructures under the naos, which have been dated as early as the 6th century. Chora was a center of the resistance to Iconoclasm in the 8th and 9th centuries, with the iconodule saint Michael Synkellos serving as its abbot. Other iconodule saints were buried there, including deposed Patriarch Germanos and Theophanes Graptos. 
The first phase of the current structure dates to the 11th century, when Maria Doukaina, the mother-in-law of Alexios I, restored the monastery around 1077-1081. Chora was again renovated in the 12th century (perhaps after being damaged by an earthquake) by the sebastokrator Isaac Komnenos (depicted in the Deesis mosaics in the inner narthex), when it took the form of an atrophied Greek cross. Isaac Komnenos, the younger brother of Emperor John II (1118-1143), had a tomb built at Chora, though he was later buried at the Kosmosoteira Monastery in Bera (modern Feres, Greece). Patriarch Kosmas was also buried at Chora in 1081. Chora was either damaged or falling into ruin during the Latin Occupation of Constantinople (1204-1261). The scholar Maximos Planudes and Patriarch Athanasios both commented on its poor state after the city was reconquered. The nun Melane (formerly Maria, daughter of Emperor Michael VIII) made donations to the monastery and might have sponsored some repairs around this time, as she is depicted in the Deesis mosaic in the inner narthex.
Theodore Metochites began to restore Chora on a grand scale around 1315. He was first the minister of the treasury when he began the project and subsequently was promoted to be the grand logothete (1316-1321). He was also one of the greatest scholars of his era and the first non-imperial founder of a monastery in the Late Byzantine era. His portrait is located above the entrance to the naos (nave), where he is depicted offering the church to Christ. The church was extensively rebuilt and lavishly decorated with mosaics and frescoes by Metochites. The monastery he refounded was endowed with substantial estates, as well as a hospital and a public kitchen. He also donated his extensive collection of books, making it the most comprehensive library of Constantinople in the Late Byzantine era. After falling from power in 1328 and being exiled from the city for two years, he returned to Chora as a monk and was buried there in 1332. Several other Late Byzantine elites, including Michael Tornikes and his wife (monk Makarios and nun Eugenia), were also buried at Chora. 
Chora was one of the first churches to be looted when the Ottomans conquered the city in 1453. According to one tradition, the icon of the Virgin Hodegetria, which was stored in Chora in 1453, was cut into pieces by Ottoman soldiers who entered the city through the Gate of Adrianople. Chora was converted into a mosque during the reign of Bayezid II by the grand vizier Atik Ali Pasha before 1511, who founded its religious endowment (vakf). It became known as (Ali Pasha) Kenise Mosque or Kariye Mosque (from the Arabic translation of Chora). At this time, a mihrab was added, while its belfry was demolished and replaced by a minaret. The mosaics and frescoes were partially covered with plaster around the 17th or 18th century. Mustafa Agha was responsible for building the nearby fountain in 1668. In the 18th century, the Chief Eunuch (Kızlarağa) Beshir Agha established an imaret (soup kitchen) and a school, both of which no longer survive. It was substantially repaired by the architect Ismail Halife after being damaged by an earthquake in 1766. It was also restored after the earthquake of 1894, which severely damaged the building and caused the minaret to collapse. Kariye gave its name to the local neighborhood (mahalle), the urban administrative unit located here.

By the late 19th century, it became popular with Western tourists, during which time it became known as the “Mosaic Mosque”. In 1945 Chora was turned into a museum and placed under the jurisdiction of the Ayasofya Museum. Starting in 1947, the Byzantine Institute of America (and later the Dumbarton Oaks Field Committee) began the conservation of Chora, cleaning the mosaics and frescoes and restoring the building. Its current restoration began in 2013. In 2020, it was officially converted into a mosque, though it is now closed. 

See also: Pammakaristos Monastery